Thesis (Ph.D.) - Cairo University - Faculty of Physical Therapy - Department of Basic Science

Background: Obesity is a chronic disease characterized by excessive body fat that causes damage to the individual's health and is associated with comorbidities such as Diabetes mellitus, Hypertension, and Vascular dysfunction. Common traditional treatments utilized for obesity include medications, surgical interference, exercises, and diet programs. Few studies have investigated cryotherapy techniques for obesity. Purpose: To investigate the effect of cryolipolysis on leptin hormone in obese subjects.Material and Methods: thirty obese subjects from both genders had body mass index from 30 to 35, their ages ranged from 30 to 40 years old were selected. Design of study: Pre test-post test-control group was used. Group (A) the experimental group: This group consisted of 15 obese subjects were received cryolipolysis, a duration of 60 min.1 session/month for 3 months and diet intervention. Group (B)The control group: This group consisted of 15 obese subjects were received diet intervention for 3 months. All the subjects were assessed before and after treatment with body mass index, hunger level, and serum leptin hormone. Results: Within two groups: There was a significant decrease in body mass index, hunger level, and leptin hormone. In group (A) there was a significant decrease in body mass index, hunger level, and leptin hormone more than in group (B). Alpha level was set at (P<0.05).Conclusion: The application of the cryolipolysis technique on obese subjects positively affects body mass index, hunger level, and leptin hormone

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