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Analytical study of some drugs affecting nasal mucosa / Joliana Fawzy Farid Saleh ; Supervised Nadia Mohammed Mostafa , Yasmin Mohammed Fayez , Hebatallah Mohammed Essam

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Joliana Fawzy Farid Saleh , 2021Description: 185 P. : charts , facsimiles ; 25cmOther title:
  • دراسة تحليلية لبعض الأدوية المؤثرة على الغشاء المخاطى للأنف [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry Summary: This thesis is concerned with the analysis of some drugs affecting nasal mucosa namely, Paracetamol with Phenylephrine hydrochloride andParacetamol with Pseudoephedrine hydrochloride and Chlorpheniramine maleate in their combined form. It comprises application of different methods of analysis for assay of the selected drugs in their mixtures and in pharmaceutical dosage forms. Moreover, stability indicating methods for some of the selected drugswere developed and validated in presence of degradation products and impurities due to their toxicity.The proposed methods were statistically compared with official methods to confirm the claims of methods{u2019} validity.The applied techniques include spectrophotometry, chemometry, thin layer chromatography (TLC), high performance liquid chromatography (HPLC), capillary electrophoresis (CE) and ion selective electrodes (ISE).The proposed methods were simple, accurate, and reproducible, which would be feasible and sensitive for the determination of the studied drugs
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.03.Ph.D.2021.Jo.A (Browse shelf(Opens below)) Not for loan 01010110085317000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.03.Ph.D.2021.Jo.A (Browse shelf(Opens below)) 85317.CD Not for loan 01020110085317000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry

This thesis is concerned with the analysis of some drugs affecting nasal mucosa namely, Paracetamol with Phenylephrine hydrochloride andParacetamol with Pseudoephedrine hydrochloride and Chlorpheniramine maleate in their combined form. It comprises application of different methods of analysis for assay of the selected drugs in their mixtures and in pharmaceutical dosage forms. Moreover, stability indicating methods for some of the selected drugswere developed and validated in presence of degradation products and impurities due to their toxicity.The proposed methods were statistically compared with official methods to confirm the claims of methods{u2019} validity.The applied techniques include spectrophotometry, chemometry, thin layer chromatography (TLC), high performance liquid chromatography (HPLC), capillary electrophoresis (CE) and ion selective electrodes (ISE).The proposed methods were simple, accurate, and reproducible, which would be feasible and sensitive for the determination of the studied drugs

Issued also as CD

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