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Regeneration potential of bone marrow derived mesenchymal stem cells and platelet rich plasma (prp) on irradiation-induced damage of submandibular salivary gland in albino rats/ Nermine Hani Mohamed ; Supervised Sahar Shawkat , Marwa Samir Moussa , Nermeen El-moataz Bella

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Nermine Hani Mohamed , 2021Description: 149 P.: Facsmiles , charts , photographs ; 25 cmOther title:
  • تأثير الخلايا الجذعية المستمدة من نخاع العظام والبلازما الغنية بالصفيحات على إعادة تجديد الغدد اللعابية المتضرره من الاشعاع في الفئران البيضاء [Added title page title]
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Dissertation note: Thesis (M.Sc. ) - Cairo University - Faculty of Dentistry - Department of Oral Biology Summary: Aim Compare between the effects of PRP, bone marrow mononuclear cells (BMMCs) and their combination on regeneration of irradiated rat submandibular salivary glands (SMD). Methodology: 32 healthy male albino rats were irradiated with a single dose of 6 Gy then classified into four main groups of 8 rats. The rats of group A received no treatment after irradiation. Group B rats received single intraglandular injection of BMMCs (0.5{u00D7}105) cells/100oL, 24 hours (hr) after irradiation. Group C rats, received a single intraglandular injection of 100 ol of PRP 24 hr after irradiation. In group D, 24 hr after irradiation, the rats received single intraglandular injection of (0.5{u00D7}105) BMMCs suspended in 100 ol PRP supernatant. Histopathological examination of all groups was performed at 1- and 2-weeks post irradiation. The histological changes were evaluated histomorphometrically in term of total surface area percentage of acini. TGF- Ý1 expression was measured using Polymerase chain reaction (PCR).
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.12.M.Sc.2021.Ne.R. (Browse shelf(Opens below)) Not for loan 01010110085599000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai09.12.M.Sc.2021.Ne.R. (Browse shelf(Opens below)) 85599 CD Not for loan 01020110085599000
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Cai01.09.12.M.Sc.2021.Ka.L Localization of indicators for epithelial mesenchymal transformation in gingiva from chronic periodontitis patients as compared to healthy individuals : Case control study / Cai01.09.12.M.Sc.2021.Ka.L Localization of indicators for epithelial mesenchymal transformation in gingiva from chronic periodontitis patients as compared to healthy individuals : Case control study / Cai01.09.12.M.sc.2021.La.A. He Anticancer Effect Of Magnetic Selenium Based Nanocomposites On Tongue Carcinoma Stem Cells : (IN VITRO STUDY) / Cai01.09.12.M.Sc.2021.Ne.R. Regeneration potential of bone marrow derived mesenchymal stem cells and platelet rich plasma (prp) on irradiation-induced damage of submandibular salivary gland in albino rats/ Cai01.09.12.M.Sc.2022.Em.A. The Anti-inflammatory Effect of flaxseed oil on Ligature Induced Periodontitis in Mandibular Molars of Wistar Rats: An Animal Study / Cai01.09.12.M.Sc.2022.Na.P Prophylactic Effect of Theobromine on Pop Candies-induced enamel demineralization in human teeth (In vitro study)/ Cai01.09.12.Ph.D.1995.Mo.C Comperative study of dental follicular tissnes in the molars and the continously erupting incisors of allino rats /

Thesis (M.Sc. ) - Cairo University - Faculty of Dentistry - Department of Oral Biology

Aim Compare between the effects of PRP, bone marrow mononuclear cells (BMMCs) and their combination on regeneration of irradiated rat submandibular salivary glands (SMD). Methodology: 32 healthy male albino rats were irradiated with a single dose of 6 Gy then classified into four main groups of 8 rats. The rats of group A received no treatment after irradiation. Group B rats received single intraglandular injection of BMMCs (0.5{u00D7}105) cells/100oL, 24 hours (hr) after irradiation. Group C rats, received a single intraglandular injection of 100 ol of PRP 24 hr after irradiation. In group D, 24 hr after irradiation, the rats received single intraglandular injection of (0.5{u00D7}105) BMMCs suspended in 100 ol PRP supernatant. Histopathological examination of all groups was performed at 1- and 2-weeks post irradiation. The histological changes were evaluated histomorphometrically in term of total surface area percentage of acini. TGF- Ý1 expression was measured using Polymerase chain reaction (PCR).

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