Rabab Kamel Mahmoud <br/><br/>
Design of a transdermal delivery system for an analgesic drug /  
 تصميم صيغة جديدة لعقار مسكن للاستخدام عبر الجلد 
Rabab Kamel Mahmoud ; Supervised Mahmoud M.Ghorab , Hussein O.Ammar , Soheir A.Elnahhas 
 - Cairo :   Rabab Kamel Mahmoud ,   2008 
 - 392P. :   charts ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty Of Pharmacy - Department Of Pharmaceutics 
<br/><br/> Tramadol , a centrally - acting potent analgesic with weak opioid agonist activity (mainly M1 metabolite) and less side effects than other analgessics , has a half - life of 6hours , therefore , requires frequent dosing.It is freely soluble in water ; hence , judicious selection of retarding formulations is necessary 
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<br/><br/><label>Subjects--Index Terms: </label>Pain Polymers Tramadol