A pharmacological study on the effects of a calcium channel blocker and an antioxdant on the activity and toxicity of doxorubicin in tumour bearing mice /
دراسة فارماكولوجية لتأثير احد غالقات قنوات الكالسيوم واحد مضادات الأكسدة على فاعلية وسمية عقار الدوكسوروبسين فى الفئران حاملات الورم
Omaima Ali Mohamed Kholify Ahmed ; supervised Afaf A. Ain Shoka , Abdelmoneim M. Osman , Hanan Salah Eldin Elabhar
- Cairo : Omaima Ali Mohamed Kholify Ahmed , 2008
- 177 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology
Doxorubiin(DXR)is one of the most commonly used anticancer drugs nevertheless cardiotoxicity myelo - suppression and nephrotoxicity besides the development of tumour resistane have limited its clinical use verapamil(VRP)was chosen to overcome tumour resistance and selenium(SE)is a known antioxidant and a free radical scavenging micronutrient