TY - BOOK AU - Heba Hamed Rashad AU - Reem Emad TI - Prospective phase ii study of hypofractionated short course radiation therapy folowed by neoadjuvant chemotherpy and surgery in locally advanced rectal cancer U1 - 610 PY - 2022/// KW - RadiationOncology KW - Radiation Therapy N1 - Thesis (Ph.D)-Cairo University,2022; Bibliography: p. 105-116 N2 - Upfront neoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy remained a standard of care for loclly advanced rectal cancers. However this strategy is associated with high rates of distant failure. Total neoadjuvant therapy with short course radiation therapy (SCRT) followed by full course of chemotherapy is investigated aiming for early treatment of micrometastasis and reducing rates of distant failure without compromising local control UR - http://172.23.153.220/th.pdf ER -