TY  - GEN
AU  - Mona Mohamed Abdelhakim
AU  - Hamdy Mahmoud Hassaneen , 
AU  - Mohamed Ali Eldesoukey , 
AU  - Samar Kamal Kassim , 
TI  - Vascular endothelial growth factor and her - 2 / neu in breast cancer / 
PY  - 2004///
CY  - Cairo : 
PB  - Mona Mohamed Abdelhakim , 
KW  - HER2 - neu
KW  - VEGF
N1  - Thesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Biochemistry; Issued also as CD
N2  - Breast cancer represents an important problem in Women oncology A growing tumor induces the host endothelial cells to proliferate and supply the requisite vascular support allowing tumor development Vascular endothelial growth factor (VEGF) and HER2 - neu have been demonstrated to induce angiogenesis in epithelial tumors , this study included 45 tumors from patients with breast cancer in different grades and stages , in addition to 18 samples of benign breast lesions VEGF has been measured in the cytosolic fractions using enzyme immunoassay Tissue HER2 - neu was assessed using immunohistochemistry for its protein VEGF mean rank was significantly higher in breast cancer tumors compared to benign lesions (P=0001) Eleven samples were positive for Her2 - neu of them were in malignant group , with highest frequency in grade (IIIII) of the disease (11 / 45 , 25
UR  - http://172.23.153.220/th.pdf
ER  -