TY - BOOK AU - Hany Zakaria Mohamed, AU - Alia Hassan Abdel Fattah AU - Helmy Elghawaby AU - Akram Abdelbary AU - Wael Samy TI - The use of veno-arterial extra corporeal membrane oxygenation for hemodynamics support during high-risk percutaneous coronary intervention U1 - 616.028 PY - 2022/// KW - Critical Care KW - qrmak KW - Veno-Arterial extracorporeal membrane oxygenation KW - Percutaneous coronary intervention N1 - Thesis (Ph.D)-Cairo University, 2023; Bibliography: pages 109-118.; Issued also as CD N2 - The study is designed to assess the impact of hemodynamic support by V-A ECMO during high-risk PCI, if it shows advantages to maintain perfusion and management of any complications during the procedure. Objectives: use of VA ECMO as a hemodynamic support for complete myocardial revascularization of high-risk patients. Subjects and methods: A prospective interventional study will be performed on patients with viable ischemic myocardium, syntax score>22, excluding scarred myocardium and refused CABG. Hemodynamic support will be done during elective high-risk PCI procedure by connecting patients on V-A ECMO (Fem-Fem configuration), compared to patients had high risk PCI without mechanical circulatory support. Group 1(Study group): 10 patients underwent high risk PCI on V-A ECMO support. Group 2(Control group): 10 patients underwent high risk PCI without V-A ECMO support. Results: A case-control study total of 20 patients were identified, 10 patients underwent high risk PCI on V-A ECMO support other group (Control group) 10 patients underwent high risk PCI without V-A ECMO support. Group 1: mean age 59, mean EF 30.90%, 5 diabetic, 6 hypertensive, 4 patients had LM lesion, average of 3.9 stents, 1 patient had VT during PCI, 6 patients needed vasopressors and inotropic support, 7 patients needed surgical decannulation, 3 patients used vascular closure device, 4 patients needed invasive mechanical ventilation during PCI, 8 patients had complete revascularization in one session, 10 patients were successfully weaned off V-A ECMO support just after PCI, average ECLS duration 2.5 hrs. all patients were successfully discharged home within 1 week. Conclusion: V-A ECMO showed beneficial supportive rule for hemodynamics during high-risk PCI, minimizing risks during procedure and maintaining perfusion, high volume studies are needed to confirm benefits over conventional treatment; حالات القصور بالشرايين التاجيه المعقده و الدقيقه مع ضعف شديد بعضله القلب يجعل التدخل الجراحي و القسطره التداخليه عاليه الخطوره لهولاء المرضي , فأن هذه الدراسة تهدف الى دراسة الفوائد من استخدام جهاز الاكسجة الغشائية خارج الجسم وريدي شرياني لدعم ديناميكا الدم اثناء القيام بقسطرة تداخليه عالية الخطورة على الشرايين التاجية, تمت الدراسة بشكل استعادى لبيانات المرضى بمستشفيات جامعه القاهرة, تم تقسيم المرضى الى مجموعتين , تلقت المجموعه الاولى البروتوكول العلاجى المتبع طبقا لبروتوكولات وزارة الصحة المصرية و الارشادات العالمية و تم مقارنة النتائج بين المجموعتين ER -