Amal Ibrahim Ahmed Makhlouf <br/><br/>
A pharmaceutical study on metronidazole thermo and pH-sensitive controlled release drug delivery systems /  
 دراسة صيدلية لانظمة علاجية منتظمة الانطلاق لعقار الميترونيدازول حساسة لدرجة الحرارة ولقيمة الاس الهيدروجينى 
Amal Ibrahim Ahmed Makhlouf ; Supervised Galal M. Elmahrouk , Mona H. Abouleinien 
 - Cairo :   Amal Ibrahim Ahmed Makhlouf ,   2009 
 - 234P.:   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics 
<br/><br/> This thesis aims to use chitosan to design and optimize thermo and pH sensitive hydrogels for metronidazole.The prepared thermosensitive hydrogel is an in -situ gelling system for the subcutaneous adminstration of metronidazole for the eradication of Demodex mite wich has an essential role in the pathogenesis of rosacea 
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<br/><br/><label>Subjects--Index Terms: </label>Hydrogels Metronidazole pH-sensitive