Neama Ahmed Mohamed

Synthesis and biological evaluation of some novel quinazoline derivatives / التشييد والتقييم البيولوجى لبعض مركبات الكينازولين الجديدة Neama Ahmed Mohamed ; Supervised Abd El samea Mahmoud Abd El fattah , Emad Mohamed Kassem - Cairo : Neama ahmed Mohamed , 2005 - 136P : ill ; 30cm

Thesis (PH.D.) - Cairo University - Faculty Of Science - Department Of Organic Chemistry

This work has been carried out to investigate some new quinazoline derivatives incorporated into another heterocyclic moieties like thiazolidine , pyrazoline , isoxazoline , pyrimidine and pyridine hoping to obtain more active and less toxic compoundsThe structures of all compounds were confirmed and established by chemical and spectroscopic methodsSome of the new compounds were tested against Gram - ve and Gram+ve bacteria , yeast and fungi and some compounds tested as antiinflammatory agentsAlso , we study the effect of some compounds as anticancer agents



isoxazoline Oxazine pyrazoline quinazoline