TY - GEN AU - Marwa Abd El Malek Nassar AU - Dalia Basiony , AU - Mohsen Soliman , AU - Shahira Ramadan , TI - Treatment of melasma with topical vitamin c and trichloroacetic acid versus trichloroacetic acid alone : : comparative study / PY - 2006/// CY - Cairo : PB - Marwa Abd El Malek Nassar , KW - Chemical peeling KW - Melasma KW - Retinoic acid KW - Sunscreens KW - Trichloroacetic acid hydroquinone cream KW - Vitamin C N1 - Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Dermatology and Venerology; Issued also as CD N2 - Melasma is an acquired pigmentary disorder with irregular macular lesions that varies from light to dark brown or grey - brownThe face and the other sun exposed areas are the sites of affectionImportant probable causes : hormonal factors ; as pregnancy and contraceptive pills , sun exposure or idiopathicDifferent treatment modalities have been used for the treatment of melasma including : topical treatment using sunscreens , alpha hydroxy acids , retinoids , vitamin C , vitamin E , azelaic acid cream , kojic acid and skin bleaching creams containing hydroquinone 2 and 4Chemical peeling using glycolic acid , phenol and trichloroacetic acid (TCA) have been also usedOther treatment modalities include laser and dermabrasionWe treated 30 cases of melasma in our study , all were femalesThey were all primed with hydroquinone cream , retinoic acid and all were advised to avoid sun exposure as much as possible and use sun screensGroup (A) used trichloroacetic acid as a chemical peeling alone , while we added vitamin C topically in group (B) , which showed better results and delayed recurrenc , e ER -