Study on diltiazem hydrochloride controlled-release dosage forms /
دراسة على الاشكال الصيدلية المنضبطة الانطلاق لعقار هيدروكلوريد الديلتيازيم
Ahmed Abdelrahman M. A. Elashmawy ; Supervised Nadia M. Mursi , Rania M. Badr Eldeen
- Cairo : Ahmed Abdelrahman Mohamed Ahmed Elashmawy , 2009
- 258P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
Diltiazem hydrochloride is a calcium channel blocker drug and widely prescribed at relatively high doses for the treatment of hypertension and angina. It is a freely water- soluble drug. The short half- life of diltiazem ranging from 3 to 5 hours requires multipe daily drug dosage in order to maintain adequate plasma concentrations