TY - BOOK AU - Ahmed Abdelrahman Mohamed Ahmed Elashmawy AU - Nadia Mohamed Mursi , AU - Rania Mohamed Badr Eldeen , TI - Study on diltiazem hydrochloride controlled-release dosage forms / PY - 2009/// CY - Cairo : PB - Ahmed Abdelrahman Mohamed Ahmed Elashmawy , KW - Controlled- Release KW - Diltiazem Hydrochloride KW - Gel- Matrix Tablets N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics; Issued also as CD N2 - Diltiazem hydrochloride is a calcium channel blocker drug and widely prescribed at relatively high doses for the treatment of hypertension and angina. It is a freely water- soluble drug. The short half- life of diltiazem ranging from 3 to 5 hours requires multipe daily drug dosage in order to maintain adequate plasma concentrations UR - http://172.23.153.220/th.pdf ER -