Comparative study on cytogenetic and molecular biomarkers of heavy metal toxicity in the laboratory mice(Mus Musculus) /
دراسة مقارنة على مؤشرات وراثية وخلوية وجزيئية للتسمم بالمعادن الثقيلة فى فئران المعمل(مس ماسكيولس)
Haidan Mostafa Salem Elshorbagy ; Supervised Mohamed Akmal A. Elghor , Magada Mohamed Noshy , Mohamed Hussein Awwad
- Cairo : Haidan Mostafa Salem Elshorbagy , 2009
- 108Leaves : facsimiles ; 30cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology
The induction of micronuclei in mice bone marrow cells and point mutation at the restriction sites of 8 different restricition enzymes five cutters (Ball,Bcll, Bglll, HindIII and PstI) and three non cutters (BamHI, EcoRl and Ncol) of mice MT - l gene were investigated. Cadmium chloride was administered to adult male mice as single i.p dose of 2.5 and 1.25 mg\kg b.w and as repeated i.p doses of 1.25 mg\kg b.w. for 4 week at 72h intervals