Tarek Ibrahim Abdelgalil

Toxic effect of cisplatinum on the liver of adult albino rat and the possible protective role of vitamin E : Light and electron microscopic study / التأثير السمى لعقار السيسبلاتينيوم على كبد الفأر الابيض البالغ والدور الوقائى المحتمل لفيتامين "هـ" : دراسة بالمجهرين الضوئى والالكترونى Tarek Ibrahim Abdelgalil ; Supervised Saber Ibrahim Shona , Abdelwakil Essawy , Sherif Mohamed Zaky - Cairo : Tarek Ibrahim Abdelgalil , 2009 - 122P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Anatomy

Cisplatinum is one of the most effective antineoplastic druge used in the treatment of ovarian testicular and head and neck tumors but it has undesirable toxic effects on the liver at high doses . The present study was designed to detect the toxic effect of the cisplatinum on the liver in the adult albino rats and the possible protective role of vitamin E in prevention of such toxicity



Cisplatinum Oxidative stress Vitamin E