TY - BOOK AU - Marwa Salah Farhan AU - Aisha Mostafa Abdelrahman , AU - Eman Refaat Elmahgoub , AU - Nesren Mohamed Elgharbawy , TI - Nucleophosmin gene mutation in de novo acute myeloid leukaemia / PY - 2009/// CY - Cairo : PB - Marwa Salah Farhan , KW - Acute myeloid leukaemia KW - Gene mutation KW - Nucleophosmin N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD N2 - Somatic mutation nucleophosmin gene (NPMI) has been reported in acute myeloid leukaemia (AML) . In the present study , NPMI mutation was investigated by reverse trascriptase - PCR (RT-PCR) in 27 patients with de novo AML as well as 10 normal subjects as a control group . Internal tandem duplication mutation of Fms- like tyrosine kinase 3 (FLT3/ITD) and length mutation of FLT3 (FLT3/LM) were also analyzed UR - http://172.23.153.220/th.pdf ER -