Yasmin Mohamed Mahmoud Syam <br/><br/>
Synthesis of certain New quinazoline derivatives of expected anti-inflammatory activity /  
 تشييد بعض مركبات الكينازولين الجديدة المتوقع لها فاعلية مضادة للالتهابات 
Yasmin Mohamed Mahmoud Syam ; Supervised Kamelia Mahmoud Amin , Mohsen Mohamed Kamel 
 - Cairo :   Yasmin Mohamed Mahmoud Syam ,   2010 
 - 158 P. :   charts ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry 
<br/><br/> Quinazoline derivatives are of considerable chemical and pharmacological importance as therapeutic agents. Various quinazoline possess, among other biological activities, anti-inflammatory and analgesic properties. Accordingly, the present investigation is concerned with the synthesis of novel series of 3-(4-substituted phenyl_-spiro[(2H,3H)-quinazoline-2,1'-cyclohexan]-4)1H)-ones with the objective of discovering novel and potent anti-inflammatory and analgesic agents, that might be devoid of the gastrointestinal side effects 
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<br/><br/><label>Subjects--Index Terms: </label>Analgesic Anti-inflammatory Spiro quinazolinones