TY - BOOK AU - Yasmin Mohamed Mahmoud Syam AU - Kamelia Mahmoud Amin , AU - Mohsen Mohamed Kamel , TI - Synthesis of certain New quinazoline derivatives of expected anti-inflammatory activity / PY - 2010/// CY - Cairo : PB - Yasmin Mohamed Mahmoud Syam , KW - Analgesic KW - Anti-inflammatory KW - Spiro quinazolinones N1 - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry; Issued also as CD N2 - Quinazoline derivatives are of considerable chemical and pharmacological importance as therapeutic agents. Various quinazoline possess, among other biological activities, anti-inflammatory and analgesic properties. Accordingly, the present investigation is concerned with the synthesis of novel series of 3-(4-substituted phenyl_-spiro[(2H,3H)-quinazoline-2,1'-cyclohexan]-4)1H)-ones with the objective of discovering novel and potent anti-inflammatory and analgesic agents, that might be devoid of the gastrointestinal side effects ER -