Noha Ramadan Ibrahim Ahmed

Effect of a novel compound (1- buty 1 - 3 - [2E - 3 - (dimethylamino) prop - 2 - enoy1] - 4 - hydroxyguinolin - 2(1H)-one) (B D H Q ) against schistosoma mansoni in experimental animals / تأثير مركب (1- بيوتيل -3-1 ]E2-3-(ثنائى ميثيل امينو )( بروب -2- اينويل [4- هيدروكسى كينولين -2- 1H -اون )BDHQ) على دودة البلهارسيا المعوية فى حيوانات التجارب) Noha Ramadan Ibrahim Ahmed ; Supervised Fathy Abdelghaffar , Abdelrahman Bashtar , Amal Elshennawy - Cairo : Noha Ramadan Ibrahim Ahmed , 2010 - 95Leaves : charts , facsimiles ; 30cm

Thesis (M.Sc.) - Cairo University - Faculty of science - Department of Zoology

the effect of treatment of murine schistosomiasis with a novel compound (BDHQ) administrated alone and combined with PZQ . Oral administrated of BDHQ post infection led to a statistically significant decrease in schistosoma mansoni worm burden and number of ova/g tissue (hepatic and intestinal ). Ultrastructural examination of the treated worms revealed detachment and / or implantation of the spines within the vesiculated and degenerated tegument in all treated groups in comparison to untreated control



BDHQ Praziquantel (PZQ) Schistosomiasis