TY - BOOK AU - Noha Ramadan Ibrahim Ahmed AU - Abdelrahman Bashtar , AU - Amal Elshennawy , AU - Fathy Abdelghaffar , TI - Effect of a novel compound (1- buty 1 - 3 - [2E - 3 - (dimethylamino) prop - 2 - enoy1] - 4 - hydroxyguinolin - 2(1H)-one) (B D H Q ) against schistosoma mansoni in experimental animals / PY - 2010/// CY - Cairo : PB - Noha Ramadan Ibrahim Ahmed , KW - BDHQ KW - Praziquantel (PZQ) KW - Schistosomiasis N1 - Thesis (M.Sc.) - Cairo University - Faculty of science - Department of Zoology; Issued also as CD N2 - the effect of treatment of murine schistosomiasis with a novel compound (BDHQ) administrated alone and combined with PZQ . Oral administrated of BDHQ post infection led to a statistically significant decrease in schistosoma mansoni worm burden and number of ova/g tissue (hepatic and intestinal ). Ultrastructural examination of the treated worms revealed detachment and / or implantation of the spines within the vesiculated and degenerated tegument in all treated groups in comparison to untreated control ER -