TY  - BOOK
AU  - Marwa Galal Eldin Elgazzar 
AU  - Fatma Abdelfattah Ragab , 
AU  - Helmi Ismail Heiba , 
AU  - Mostafa Mohamed Soliman Ghorab , 
TI  - Synthesis of new pyrrole pyrazole pyrimidine and pyrrolopyrimidine derivatives carrying a sulfonamide moiety of expected antitumor activity: with studying the synergistic effect of y - irradiation / 
PY  - 2010///
CY  - Cairo : 
PB  - Marwa Galal Eldin Elgazzar , 
KW  - Pyrazole
KW  - Pyrimidine
KW  - Sulfonamide
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry; Issued also as CD
N2  - In a search for new cytoloxic agents with improved antitumor activity some new pyrrole pyrazole pyrimidine and pyrrolo [2,3-d] pyrimidine derivatives bearing sulfonamide moiety were synthesized . All the newly synthesized compounds were subjected to in - vitro cytotoxic screening also the synergism of the synthesized compounds with radiation was studied . These new compounds were docked in the active site of the carbonic anhydrase enzyme
ER  -