Dalia Mohamed Abdelhalim

A study of melanocytes, melanocyte precursor cells and stem cell factor in responding and resistant lesions of vitiligo before and after photochemotherapy / دراسة للخلايا الصبغية والخلايا ماقبل الصبغية وعامل الخلايا الجذعية فى إصابات البهاق التى تستجيب والتى لا تستجيب للعلاج الضوئى الكيميائى Dalia Mohamed Abdelhalim ; Supervised Samia Mohamed Esmat , Amira Mohamed Eltawdy , Gamal Abdelaty Hafez - Cairo : Dalia Mohamed Abdelhalim , 2009 - 186P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

PUVA therapy has long been considered a standard line of treatment for vitiligo that can stimulate melanogenesis . The response to PUVA therapy has always been deficient in some anatomical sites including hands, feet and periorificial areas . Treatment of these areas has always been a therapeutic challenge . To clarify causes of resistance at those sites by studying the expression of stem cell factor on keratinocytes and c - kit receptor on melanocytes in both resistant and responding lesions of vitiligo before and after photochemotherapy



Kit SCF \ c Vitiligo