Dendritic celle vaccine for the treatment of chronic myeloid leukemia /
مصل من الخلايا الفرعية لعلاج اللوكيميا الميلودية المزمنة
Rania Abdalla Hussein Abouelnour ; Supervised Mervat Mohamed Saad Elansary , Mervat Mohammed Wagih Mattar , Shereen Mahmoud Kamel Shawky
- Cairo : Rania Abdalla Hussein Abouelnour , 2009
- 187P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Dendritic celle (DCs) are peripheral blood and bone marrow derived antigen - presenting cells responsible for the initiation of immune responses . Because dendritic cells are clinically well tolerated it makes them interesting candidates for anti-tumor or anti - leukemic strategies . The aim of this study was to generate a dendritic cell vaccine (DC vaccine) experessing leukemia antigens by differentiating dendritic celle from myeloid blasts of chronic myeloid leukemia patients to boost their immune system and improve their clinical outcome
Adjuvant therapy Chronic myeloid leukemia Dendritic celle