TY  - BOOK
AU  - Islam Tariq Eddiasty
AU  - Hilde Spahn - Langguth , 
AU  - Laila Gamal Mahran , 
AU  - Raimund Niess , 
TI  - Baclofen derivatives : : Structural parameters vs. receptor sffinities and physicochemical properties as predicted from BCS characteristics / 
PY  - 2009///
CY  - Cairo : 
PB  - Islam Tariq Eddiasty , 
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
N2  - Baclofen a specific (gamma amino - butyric acid ) GABA B receptor agonist has successfully been used for decades for the treatment of spastic movement especially in instances of spinal cord injury spastic diplegia and multiple sclerosis . On the other hand the drug suffers from poor availabililty at the site of action the CNS despite its excellent intestinal absorption
UR  - http://172.23.153.220/th.pdf
ER  -