Doaa Sedky Mohammed ALy <br/><br/>
Immunisation against caseous lymphadenitis in sheep :   A protective efficacy of immunogenic 40 kilodalton protein of Corynebacterium pseudotuberculosis. /  
 مناعة ضد السل الكاذب فى الاغنام : القدرة الوقائية للبروتين المناعى 40 - كيلو دالتون لميكروب كورينى باكتيريم السل الكاذب 
Doaa Sedky Mohammed ALy ; Supervised WagihGad Elsaid , Magdy Ghoneim , Nabila Degheidy 
 - Cairo :   Doaa Sedky Mohammed ALy ,   2006 
 - 169P :   ill ;   30cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty Of Veterinary Medicine - Department Of Microbiology , Bacteriology , Mycology and Immunology 
<br/><br/> 40 - kDa protein was purified from concentrated culture supernatant of Cpseudotuberculosis using hydrophobic interaction chromatographyFour different vaccines were investigated for their efficiency in protecting sheep against CpseudotuberculosisVaccine composed of purified 40 - kDa protein , Vaccine composed of recombinant mutant phospholipase - D (PLD) , Vaccine composed of purified 40 - kDa protein plus recombinant mutant PLD , and Vaccine composed of formalin - killed Cpseudotuberculosis plus recombinant mutant PLDThe present study concluded that the combined vaccine composed of 40 - kDa protein plus recombinant mutant PLD succeeded in stimulating both humoral and cell mediated immune response and provided a high level of protection against CLA in sheep 
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<br/><br/><label>Subjects--Index Terms: </label>40 - kDa protein recombinant mutant PLD sheep Vaccine