TY - GEN AU - Doaa Sedky Mohammed ALy AU - Magdy Ghoneim , AU - Nabila Degheidy , AU - Wagih Gad Elsaid , TI - Immunisation against caseous lymphadenitis in sheep : : A protective efficacy of immunogenic 40 kilodalton protein of Corynebacterium pseudotuberculosis. / PY - 2006/// CY - Cairo : PB - Doaa Sedky Mohammed ALy , KW - 40 - kDa protein KW - recombinant mutant PLD KW - sheep KW - Vaccine N1 - Thesis (M.Sc.) - Cairo University - Faculty Of Veterinary Medicine - Department Of Microbiology , Bacteriology , Mycology and Immunology; Issued also as CD N2 - 40 - kDa protein was purified from concentrated culture supernatant of Cpseudotuberculosis using hydrophobic interaction chromatographyFour different vaccines were investigated for their efficiency in protecting sheep against CpseudotuberculosisVaccine composed of purified 40 - kDa protein , Vaccine composed of recombinant mutant phospholipase - D (PLD) , Vaccine composed of purified 40 - kDa protein plus recombinant mutant PLD , and Vaccine composed of formalin - killed Cpseudotuberculosis plus recombinant mutant PLDThe present study concluded that the combined vaccine composed of 40 - kDa protein plus recombinant mutant PLD succeeded in stimulating both humoral and cell mediated immune response and provided a high level of protection against CLA in sheep UR - http://172.23.153.220/th.pdf ER -