Mahmoud Aly Mohamed Ayoub

Prognostic significance of molecular markers in acute myeloid leukemia Essay / أهمية الدلالات الجزيئية فى التطور المرضى لسرطان الدم الميلودى الحاد Mahmoud Aly Mohamed Ayoub ; Supervised Safaa Mostafa Elkaraksy , Nahed Abdelwahab Mohamed , Maha Abdelhamid Eltaweel - Cairo : Mahmoud Aly Mohamed Ayoub , 2010 - 177 P. : facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Molecular markers; molecular genetic alterations are of high predictive and prognostic significance in acute myeloid leukemia (AML) especially in AML patients with normal karyotype which is the target subgroup in AML. They are providing targets for molecular therapy. The identification of molecular genetic alterations such as gene mutations or deregulated gene expression in acute myeloid leukemia (AML), has greatly advanced our understanding of leukemogenesis



Acute myeloid leukemia Cytogenetically normal AML Molecular markers