New approaches for the synthesis of hydrazone derivatives with potential pharmaceutical uses /
اتجاهات حديثة لتحضير مشتقات الهيدرازون ذات الاستخدامات الدوائية المتوقعة
Maha Abdelmejeed Mahmoud Salem ; Supervised Sherif Morad Sherif , Raafat Milad Mohareb
- Cairo : Maha Abdelmejeed Mahmoud Salem , 2010
- 101 P. ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
Cyano acetyl hydrazine (1) reacts with 9-fluorenone (2) in 1, 4-dioxan containing a catalytic amount of hydrochloric acid to form the hydrazine-hydrazone 3. compound 3 reacted with benzene diazonium chloride at 0-5 C to give the corresponding phenyl hydrazo derivative 4. Compound 4 reacted with rthyl cyanoacetate to give the pyridazine derivative 7