Fatma Baiuomy Rashedy Abdallah <br/><br/>
Antibody directed enzyme prodrug therapy :   Molecular studies on carboxypeptidase G2 , production by DNA shuffling of novel variants of CPG2 for more efficient cancer treatment /  
 علاج مرض السرطان بإستخدام جسم مضاد موجه ومحمل بإنزيم الكربوكسى بيبتيديزجى2 :   دراسات جزيئية على هذا الانزيم : وانتاج مشابهات لهذا الانزيم ذو كفاءة اعلى من خلال تكنولوجيا قص وخلط وإعادة لصق الجين 
Fatma Baiuomy Rashedy Abdallah ; Supervised Abdalla M. Negm , Ahmed I. Amien  
 - Cairo :   Fatma Baiuomy Rashedy Abdallah ,   2010 
 - 246P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry 
<br/><br/> Glucarpidase (former name : carboxypeptidase G2, or CPG2 ) is a bacterial enzyme that is widely used in detoxification of the cytotoxic drug methotrexate and in Antibody Directed Enzme Prodrug Therapy ( ADEPT ) for cancer treatment . In this study we report three achievements in relation to the CPG2 enzyme and the ADEPT for cancer treatment 
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<br/><br/><label>Subjects--Index Terms: </label>ADEPT  CPG2 overexpression  Synthetic carboxypeptidase G2