TY - BOOK AU - Fatma Baiuomy Rashedy Abdallah AU - Abdalla M. Negm , AU - Ahmed I. Amien , TI - Antibody directed enzyme prodrug therapy : : Molecular studies on carboxypeptidase G2 , production by DNA shuffling of novel variants of CPG2 for more efficient cancer treatment / PY - 2010/// CY - Cairo : PB - Fatma Baiuomy Rashedy Abdallah , KW - ADEPT KW - CPG2 overexpression KW - Synthetic carboxypeptidase G2 N1 - Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry; Issued also as CD N2 - Glucarpidase (former name : carboxypeptidase G2, or CPG2 ) is a bacterial enzyme that is widely used in detoxification of the cytotoxic drug methotrexate and in Antibody Directed Enzme Prodrug Therapy ( ADEPT ) for cancer treatment . In this study we report three achievements in relation to the CPG2 enzyme and the ADEPT for cancer treatment UR - http://172.23.153.220/th.pdf ER -