TY - BOOK AU - Marwa Ahmed Naguib Mohamed AU - Amany A. Tohamy , AU - Magda Mohamed Noshy , AU - Mahmoud Ahmed M. Amer , TI - Assessment of the role of lipoic acid in modulating the genotoxic effects of copper sulphate in mice / PY - 2010/// CY - Cairo : PB - Marwa Ahmed Naguib Mohamed , KW - Chromosomal aberrations KW - Copper sulphate KW - Lipoic acid N1 - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology; Issued also as CD N2 - The assumption of oxidative stress as a mechanism in copper toxicity suggests that antioxidants might play a role in the treatment of copper poisoning . The present study was designed to evaluate the efficacy of alphalipoic acid ( LA ) protection against chromosomal damage induced by copper sulphate in bone marrow cells of mice using two cytogenetic end points, chromosomal aberrations analysis ( CAs ) and micronucleus ( MN ) test ER -