Gene therapy of hematological maligancies /
العلاج الجينى لسرطانات الدم
Mohamed Mahmood Ahmed Nadeem ; Supervised Manal Mohamed Wagdey Elmaserey , Heba Nabil Abdelrazak
- Cairo : Mohamed Mahmood Ahmed Nadeem , 2007
- 140P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty Of Medicine - Department Of Clinical and Chemical Pathology
This aims to transfer a gene that becomes the normal host tissue less senstivite to cytotoxic drug.But we must the leukemia cells from gain a MDR gene.Trying to transfer MDR to normal hemopoietic cells to save it from the effect of cytotoxic drugs.The mest famous one is MDR - 1 transfer DHFR gene transfer