TY - BOOK AU - Rehab Abdelwadod Abdelfatah AU - Dina Hesham , AU - Heba Mohamed Sharaf Eldeen , AU - Nermine Bahgat , TI - Significance of hepatocyte growth factor ( HGF ) concentrations in serum of patients with liver cirrhosis and patients with hepatocellular carcinoma / PY - 2010/// CY - Cairo : PB - Rehab Abdelwadod Abdelfatah , KW - Alpha fetoprotein KW - Hepatocyte growth factor KW - Liver cirrhosis and hepatocellular carcinoma N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD N2 - HGF is a heterodimer composed of an alpha - chain subunit ( 69 kDa ) and a beta - chain subunit ( 34kDa ) which are linked by a disulfide bond . Although HGF was initially identified as a potent mitogen for hepatocytes , considerable evidence indicates that intracellular signaling pathways driven by HGF - c - Met receptor coupling leads to multiple biological responses in a variety of cells , including mitogenic , motogenic , morphogenic and antiapoptotic activities ER -