Physiological and molecular study of autosomal dominant neurodegenerative diseases : Huntington's disease and spinocerebellar ataxias in Egyptian patients /
دراسة فسيولوجية وجزيئية لأمراض تحلل المخ ذات الصفة السائدة : مرض هنتينجتون وأمراض الترنح الشوكى المخيخى فى المرضى المصريين
Nahla Nagah Eldin Ibrahim ; Supervised Said M. Rawi , Alice K. Abdelaleem , Nermeen A. Kishk
- Cairo : Nahla Nagah Eldin Ibrahim , 2010
- 178P. : charts, facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology
Huntington's disease (HD) and spinocerebellar ataxias are autosomal dominant neurodegenerative diseases that elicit several pathological symptoms including movement abnormalities cognitive and behavioral impairments . It was revealed that all genes associated with these genetic disorders contain CAG repeats in their coding region whose expansions are the major cause of disease progression