Nahla Nagah Eldin Ibrahim

Physiological and molecular study of autosomal dominant neurodegenerative diseases : Huntington's disease and spinocerebellar ataxias in Egyptian patients / دراسة فسيولوجية وجزيئية لأمراض تحلل المخ ذات الصفة السائدة : مرض هنتينجتون وأمراض الترنح الشوكى المخيخى فى المرضى المصريين Nahla Nagah Eldin Ibrahim ; Supervised Said M. Rawi , Alice K. Abdelaleem , Nermeen A. Kishk - Cairo : Nahla Nagah Eldin Ibrahim , 2010 - 178P. : charts, facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology

Huntington's disease (HD) and spinocerebellar ataxias are autosomal dominant neurodegenerative diseases that elicit several pathological symptoms including movement abnormalities cognitive and behavioral impairments . It was revealed that all genes associated with these genetic disorders contain CAG repeats in their coding region whose expansions are the major cause of disease progression



Autosomal dominant dominant spinocerebella ataxia Huntington's disease Polymerase chain reaction