TY - BOOK AU - Nahla Nagah Eldin Ibrahim AU - Alice Kamal Abdelaleem , AU - Nermeen Adel Kishk , AU - Said Mohamed Rawi , TI - Physiological and molecular study of autosomal dominant neurodegenerative diseases : : Huntington's disease and spinocerebellar ataxias in Egyptian patients / PY - 2010/// CY - Cairo : PB - Nahla Nagah Eldin Ibrahim , KW - Autosomal dominant dominant spinocerebella ataxia KW - Huntington's disease KW - Polymerase chain reaction N1 - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology; Issued also as CD N2 - Huntington's disease (HD) and spinocerebellar ataxias are autosomal dominant neurodegenerative diseases that elicit several pathological symptoms including movement abnormalities cognitive and behavioral impairments . It was revealed that all genes associated with these genetic disorders contain CAG repeats in their coding region whose expansions are the major cause of disease progression ER -