TY - BOOK AU - Mohammed Toama Almasri AU - Hesham Samy Sadek , AU - Naywa Othman , AU - Rania Hassan Khalefa , TI - Effect of smoking on the level of matrix metalloprotiense - 8 in the gingival crevicular fluid of patient with chronic periodontitis = : تأثير التدخين على مستوى الميتالوبروتينيز - 8فى السائل الميزابى اللثوى فى مريض الألتهابات المزمنة فى الأغشية المحيطة بالأسنان/ PY - 2010/// CY - Cairo : PB - Mohammed Toama Almasri , KW - Chronic periodontitis KW - Matrix metalloprotiense-8 KW - Smoking N1 - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology; Issued also as CD N2 - Matrix metallopropteinase ( MMP ) - 8, collagenase - 2, is a key mediator of irreversible tissue destruction in chronic periodontitis and detectable in gingival crevicular fluid ( GCF ) . MMP - 8 mostly originates from neutrophil leukocytes , the first line of defence cells which exist abundantly in GCF , especially in inflammation ER -