Zeta associated protein-70 : A new marker in chronic lymphphocytic leukemia /
البروتين المرتبط بزيتا - 70: دليل جديد في سرطان الخلايا الليمفاوية المزمن
Shereen Ahmed Tolba ; Supervised Enas Esmail Raafat , Hala Mohammad Farawela , Hamdy Mohamed Zawam
- Cairo : Shereen Ahmed Tolba , 2010
- 219 P. : charts ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
B-cell chronic lymphocytic leukaemia (B-CLL) is a disease with a highly variable clinical course; some patients never need treatment, while others require intensive treatment early after diagnosis. Some new prognostic factors, such as ZAP-70 and the expression of CD38 in leukemic cells were introduced to identify attenuated versus progressive types of CLL bearing the potential to facilitate risk-adapted treatment strategies