TY - BOOK AU - Doaa Boshra Abdulfattah Farag AU - Amal Abdelhaleem Mohamed Eissa , AU - Ashraf Mostafs Kamal Hassan Abadi , TI - Design of non-atp competitive inhibitors of polo-like kinases through "Replace" / PY - 2010/// CY - Cairo : PB - Doaa Boshra Abdulfattah Farag , KW - Anti-tumor KW - Polo-box domain KW - Protein kinase inhibitors N1 - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry; Issued also as CD N2 - Application of REPLACE technique to develop peptide-small molecule hybrids as polo-box domain inhibitors, using computational chemistry methods with discovery studio 2.1 software, 14 structures were synthesized by solid phase synthesis using Fmoc methodology, and purification techniques with HPFC and HPLC methods UR - http://172.23.153.220/th.pdf ER -