Jowiria Aboelela Said <br/><br/>
In vitro stimulation of hemoglobin F production in thalassemic patients by the histone deacetylase inhibitor apicidin /  
 تحفيز دوالى خارجى جديد للهيموجلوبين اف فى حالات أنيميا البحر الأبيض المتوسط 
Jowiria Aboelela Said ; Supervised Nesrine Mohamed Elgharbawi , Iman Abdelmohsen Abdushaheen 
 - Cairo :   Jowiria Aboelela Said ,   2010 
 - 135P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology 
<br/><br/> Pharmacologic stimulation of fetal hemoglobin (HbF) expression may be a promising approach for treatment of Ý - thalassemia . The aim of the present study was to determine the effect of a histone deacetylase inhibitor Apicidin on HbF production in Ý - thalassemic - cultured erythroid precursor cells . The study was conducted on twenty five Ý - thalassemic patients 
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<br/><br/><label>Subjects--Index Terms: </label>HbF  Histone deacetylase inhibitor  Ý - thalassemia