Niveen Mahmoud Mostafa Sharawy

Study of the effect of female sex hormones on hypothalamo - pituitary - adrenal axis response to local and systemic inflammatory states / دراسة تأثير هرمونات الجنس الانثوية على استجابة المحور الهيبوثلامى النخامى الكظرى لحالات الالتهاب الكلى والموضعى Niveen Mahmoud Mostafa Sharawy ; Supervised Mohamed A. Hassan , Moshira A. H. Rateb , Laila Rashid - Cairo : Niveen Mahmoud Mostafa Sharawy , 2011 - 208P. : charts , facsimiles ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Physiology

Endotoxin is a potent activators of the hypothalamic- pituitary - adrenal (HPA) axis . However sex hormones can modulate HPA response to local and systemic inflammation . We used female rats divided in to 3 main groups : group sham group . Group cecal ligation and puncture (CLP) and group local inflamed



CLP HPA Sex hormones