Synthesis of some new bromophenylquinoline derivatives of expected anticancer activity : with studying the augmenting effect of - radiation /
تحضير بعض مشتقات البروموفينيل كينولين الجديدة والمتوقع لها نشاطا كمضادات الاورام السرطانية : مع دراسة التاثير التحفيزى لاشعة جاما
Walid Mohamed Soliman Ghorab ; Supervised Fatma Abdelfattah Ragab , Helmy Ismail Heiba
- Cairo : Walid Mohamed Soliman Ghorab , 2011
- 142 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
The present work aims to design and synthesize certain quinoline pyrimido [4,5 -b] quinoline and triazolopyrimido [4,5-b] quinoline derivatives carrying a bromo-substituent in order to explore the potential cytotoxic activity of these compounds evaluation of their anticancer activity alone and in combination with - irradiation and suggestion of their mechanism of action through a molecular docking study