Tumout necrosis factor - alpha-308 and lymphotoxin - alpha+ 252 genetic polymorphisms and the susceptibility to non - hodgkin lymphoma /
التعدد الجينى لعامل نخر الورم الفا - 308 والسم الليمفى الفا + 252 وعلاقته باحتمالات الاصابة بأورام الغدد الليمفاوية اللاهودجيكينية:
Nelly Mikhael Nasr Mikhael ; Supervised Azza Mostafa Ibrahim , Hala Aly Abdelrahman , Mervat Mamdooh Khorshied
- Cairo : Nelly Mikhael Nasr Mikhael , 2011
- 134 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
The current stdy aimed at defining the role of TNFÜ - 308 and LTÜ + 252 as genetic risk factors for NHL. The present study included 84 patients and 100 controls . Genotyping for both genes was done by PCR- RFLP technique . The study revealed that TNF-308 GG genotype can be considered as protective against acquisition NHL while TNF - 308 AA genotype can considered as risk factor for NHL. LTÜ + 252 gene polymorphism did not confer increased risk of NHL
Lymphotoxin Non - hodgkin lymphoma Tumout necrosis factor