TY - BOOK AU - Michael Naeem Andrawes AU - Fahem Abdelazem Ragab , AU - Hazem Elhameid Alakabawy , AU - Mervat Mohamed Khalaf , TI - The concept of early goal-directed therapy in sepsis syndrome / PY - 2011/// CY - Cairo : PB - Michael Naeem Andrawes , KW - APACHE IV KW - EGDT KW - Sepsis N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine; Issued also as CD N2 - Earl goal-directed therapy (EGDT) provided a consensus-derived protocol to reverse the hemodynamic disturbances by adjustment of cardiac preload, afterload, and contractility to balance oxygen delivery with oxygen demand after early identification of patients with severe sepsis and septic shock. To evaluate the concept of EGDT; provided at the earliest stage of severe sepsis and septic shock; regarding the clinical course and final outcome ER -