TY - BOOK AU - Nermeen Ahmed Hassan Abdelnabi AU - Ellham Atta Elebiary , AU - Hussein Ali Hussein , TI - Assessment of pathogenicity of the Egyptian avian influenza viruses 2008 and 2010 challenge isolates and the efficacy of H5N1 and H5N2 AIV vaccines / PY - 2011/// CY - Cairo : PB - Nermeen Ahmed Hassan Abdelnabi , KW - Challenge isolates KW - Chicken KW - Virology N1 - Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Virology; Issued also as CD N2 - HPAI local field isolates A/Chicken/Egypt/1709-6/2008 (H5NI) and A/Chicken/Egypt/1063/2010 (H5NI) were compared in their growth pattern and titers in SPF ECEs and their pathogenicities (determination of their infective and lethal doses) in chickens. H5N1 reassortant inactivated (H5N1 subtype, Egy/PR8-1 strain) and H5N2 inactivated (A/Chicken/Mexico/232/94/CPA H5N2) vaccines were compared in their ability to protection and reduce virus shedding after challenge with challenge doses 10⁵ and 10⁶ EID₅₀ of cach isolate ER -