TY - BOOK AU - Rehab Mustafa Abdelfadel AU - Amr Aly Zahra , AU - Olfat Gamil Shaker , AU - Salwa Fayez Hasan , TI - Ostcopontin gene polymorphism as marker predicting the efficacy of interferon-based therapics in patients with chronic hepatitis C / PY - 2011/// CY - Cairo : PB - Rehab Mustafa Abdelfadel , KW - HCV KW - Interferon KW - Ostcopontin N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry; Issued also as CD N2 - Viral hepatitis is T cell-mediated and ostcopontin induce T cell chemotaxis, support adhesion, proliferation, and also enhance expression of T helper 1 (Th1) cytokines. Genetic polymorphisms in the ostcopontin gene (OPN) determine the magnitude of immunity against rickettsial infection in mice. Similar polymorphisms, if present also in human beings, might affect hepatitis activity and the response to treatment by interferon and ribavirin in those infected with HCV UR - http://172.23.153.220/th.pdf ER -