Ghada Salah Ahmed <br/><br/>
Effect of silymarin and telmisartan on doxorubicin- and isoproterenol-induced cardiotoxicity in rats /  
 تأثير دوائي السليمارين و التلميسارتان على سمية القلب المحدثة تجريبيا بدوائي الدوكسوروبسن و الايزوبروتيرينول فى الجرذان البيضاء 
Ghada Salah Ahmed ; Supervised Elsaid Mahmoud Elrokh , Sawsan Abdelaziz Sadik , Ahmed Abdelrahman Ahmed 
 - Cairo :   Ghada Salah Ahmed ,   2011 
 - 148 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology 
<br/><br/> The usefulness of doxorubicin, a highly effective antitumor drug, is limited by the risk of developing cardiomyopathy. Subcellular changes leading to this toxicity are suggested to be mediated through a drug-induced increase in free radicals and lipid peroxidation. The present study was undertaken to investigate the possible protection that silymarin, an antioxidant drug, and telmisartan, angiotensin receptor bloker, can offer against doxorubicin, isoproterenol-induced cardiotoxicity 
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<br/><br/><label>Subjects--Index Terms: </label>Doxorubicin Isoproterenol Silymarin