Nahed Yehia Abdelaziz <br/><br/>
Induction of selected deletion in HA gene of Egyptian HPAI - H5N1 viruses using site directed mutagenesis /  
 تطبيقات على التطفر الموجه لاحداث ازالة فى جين التلزن الدموى لفيروسات انفلونزا الطيور سلالة( H5N1) شديدة الضراوة  
Nahed Yehia Abdelaziz ; Supervised Mohamed Abdelhameed Shalaby , Ismail Mohamed Reda , Abdelsatar Arafa 
 - Cairo :   Nahed Yehia Abdelaziz ,   2011 
 - 163 Leaves :   charts , facsimiles ;   30cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of  Virology 
<br/><br/> HA is a critical determinant of the pathogenicity of avian influenza viruses . The HA proteins of highly pathogenic H5 and H7 viruses contain multiple basic amino acids at the cleavage site that are recognized by ubiquitous proteases but low patgogenic virus contain a single arginine resdue at the HA cleavage site that are recognized by trypsin - like protease found generally at epithelial cell surfaces 
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<br/><br/><label>Subjects--Index Terms: </label>HACS HPAI 8LPAI  SDM