TY  - BOOK
AU  - Nahed Yehia Abdelaziz
AU  - Abdelsatar Arafa , 
AU  - Ismail Mohamed Reda , 
AU  - Mohamed Abdelhameed Shalaby , 
TI  - Induction of selected deletion in HA gene of Egyptian HPAI - H5N1 viruses using site directed mutagenesis / 
PY  - 2011///
CY  - Cairo : 
PB  - Nahed Yehia Abdelaziz , 
KW  - HACS
KW  - HPAI 8LPAI
KW  - SDM
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of  Virology; Issued also as CD
N2  - HA is a critical determinant of the pathogenicity of avian influenza viruses . The HA proteins of highly pathogenic H5 and H7 viruses contain multiple basic amino acids at the cleavage site that are recognized by ubiquitous proteases but low patgogenic virus contain a single arginine resdue at the HA cleavage site that are recognized by trypsin - like protease found generally at epithelial cell surfaces
ER  -