Immunohistochemical study of estrogen receptor " Ý " expression in colonic adenocarcinoma /
دراسة كيميائية نسيجية مناعية لتقييم مستقبلات هرمون الأستروجين " بيتا " فى سرطان القولون
Amany Mamdouh Abbass Abdelaziz ; Supervised Bahaa Ihab Mounir , Samia Ibrahim Elnaggar , Mohamed Faisal Darweesh
- Cairo : Amany Mamdouh Abbass Abdelaziz , 2011
- 155 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pathology
Estrogen receptor ( ER ) beta is the predominant ER in the colonic epithelium , suggesting that effects of estrogen in the colon are mediated by ER beta ER beta might reduce cell proliferation by inhibiting the cyclin D1 gene , a key factor controlling the G1 - S transition of the cell cycle and thus cell proliferation