A biopharmaceutical study on a proton pump inhibitor /
دراسة بيوصيدلية على عقار مثبط لمضخة البروتون
Ebtsam Mohammed Abdou Mohammed ; Supervised Mona Hassan Aboulelnien , Nadia Abdelkader Soliman
- Cairo : Ebtsam Mohammed Abdou Mohammed , 2012
- 190 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
Rabeprazole solium is a potent proton pump inhibitor used to relieve symptoms of gastroesophageal reflux disease (GERD) gastric ulceration and acute upper gastrointestinal bleeding . It is a prodrug which is absorbed unchanged from the intestinal wall then converted to its active form which has inhibitory effect on the ATP -as enzyme in the gastric parietal cells